Thursday, April 2, 2020

Maverakis Lab Publications



Manuscripts of special interest are in Purple
Highly downloaded papers have accompanying Altmetric Scores
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2020

Toussi A, Le ST, Barton VR, et al. Successful Management of Anti-TNF-Induced Psoriasis Despite Continuation of Therapy in a Pyoderma Gangrenosum Patient. J Drugs Dermatol. 2020;19(2):199–201. doi:10.36849/JDD.2020.4662

Cheng, Michelle & Neves, Stacey & Rainwater, Julie & Wang, Jenny & Davari, Parastoo & Maverakis, Emanual & Rea, Margaret & Servis, Mark & Nuovo, Jim & Fazel, Nasim. (2020). Exploration of Mistreatment and Burnout Among Resident Physicians: a Cross-Specialty Observational Study. Medical Science Educator. 10.1007/s40670-019-00905-z.

Shao S, Wang G, Maverakis E, Gudjonsson JE. Targeted Treatment for Erythrodermic Psoriasis: Rationale and Recent Advances [published online ahead of print, 2020 Mar 16]. Drugs. 2020;10.1007/s40265-020-01283-2. doi:10.1007/s40265-020-01283-2

Park DD, Phoomak C, Xu G, et al. Metastasis of cholangiocarcinoma is promoted by extended high-mannose glycans [published online ahead of print, 2020 Mar 25]. Proc Natl Acad Sci U S A. 2020;201916498. doi:10.1073/pnas.1916498117

Shao, Shuai & Wang, Gang & Maverakis, Emanual & Gudjonsson, Johann. (2020). Targeted Treatment for Erythrodermic Psoriasis: Rationale and Recent Advances. Drugs. 10.1007/s40265-020-01283-2.


2019


Sun Y, Reid B, Ferreira F, Luxardi G, Ma L, Lokken KL, Zhu K, Xu G, Sun Y, Ryzhuk V, Guo BP, Lebrilla CB, Maverakis E, Mogilner A, Zhao M. Infection-generated electric field in gut epithelium drives bidirectional migration of macrophages. PLOS Biology, 17(4):e3000044.

Moran A, Azghadi S, Maverakis EM, Christensen S, Dyer BA. Combined Immune Checkpoint Blockade and Stereotactic Ablative Radiotherapy Can Stimulate Response to Immunotherapy in Metastatic Melanoma: A Case Report. Cureus, 11(2): e4038.

Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S. Atopic Dermatitis is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis. The Journal of Investigative Dermatology, 139(7): 1480-1489.

Maverakis E, Le ST, Callen J, Wollina U, Marzano AV, Wallach D, Schadt C, Martinez-Alvardao YC, Cheng MY, Ma C, Merleev A, Ormerod A, Craig F, Jockenhofer F, Dissemond J, Salva K, Williams HC, Fiorentino D. New validated diagnostic criteria for pyoderma gangrenosum. Journal of the American Academy of Dermatology, 80(4): e87-e88.

Armstrong AW, Ford AR, Chambers CJ, Maverakis E, Dunnick CA, Chren MM, Gelfand JM, Gibbons CM, Gibbons BM, Lane CJ. Online Care Versus In-Person Care for Improving Quality of Life in Psoriasis: A Randomized Controlled Equivalency Trial. The Journal of Investigative Dermatology, 139(5): 1037-1044.

Ford AR, Gibbons CM, Torres J, Kornmehl HA, Singh S, Young PM, Chambers CJ, Maverakis E, Dunnick CA, Armstrong AW. Access to Dermatological Care with an Innovative Online Model for Psoriasis Management: Results from a Randomized Controlled Trial. Telemedicine Journal and e-Health, 25(7): 619-627.

Toussi A, Merleev A, Barton VR, Le ST, Marusina A, Luxardi G, Gudjonsson JE, Adamopoulos IE, Fung MA, Raychaudhuri SP, Shimoda M, Maverakis E. Transcriptome mining and a report of B cell depletion-induced psoriasis support a role for B cells in psoriasis pathophysiology. Journal of Dermatological Science, Epub ahead of print

Le ST, Merleev AA, Luxardi G, Shimoda M, Adamopoulos IE, Tsoi LC, Wang JZ, Alexanian C, Raychaudhuri SP, Hwang ST, Gudjonsson J, Marusina AI, Maverakis E2D Visualization of the Psoriasis Transcriptome Fails to Support the Existence of Dual-Secreting IL-17A/IL-22 Th17 T CellsFrontiers in Immunology, 10: 589.


Jiang G, Maverakis E, Cheng MY, Elsheikh MM, Deleage C, Méndez-Lagares G, Shimoda M, Yukl SA, Hartigan-O'Connor DJ, Thompson III GR, Estes JD, Wong JK, Dandekar S. Disruption of latent HIV in vivo during the clearance of actinic keratosis by ingenol mebutate. JCI INSIGHT, 4(7).

Le ST, Wang JZ, Alexanian C, Ellis S, Martinez-Alvarado YC, Johng S, Sood A, Maverakis EPeristomal pyoderma gangrenosum: an exceedingly rare and overdiagnosed entity? Journal of the American Academy of Dermatology, 81(1): e15.

Li Q, Kailemia MJ, Merleev AA, Xu G, Serie D, Danan LM, Haj FG, Maverakis E, Lebrilla CB. Site-Specific Glycosylation Quantitation of 50 Serum Glycoproteins Enhanced by Predictive Glycopeptidomics for Improved Disease Biomarker DiscoveryAnalytical Chemistry, 91(8): 5433-5445.

Wang EB, Kaur R, Nguyen J, Ho D, Austin E, Maverakis E, Li CS, Hwang ST, Isseroff RR, Jagdeo J. A single-blind, dose-escalation, phase I study of high-fluence light-emitting diode-red light on Caucasian non-Hispanic skin: study protocol for a randomized controlled trial. Trials, 20(1): 177.

Truong A, Le S, Kiuru M, Maverakis E. Nummular dermatitis on guselkumab for palmoplantar psoriasisDermatologic Therapy, 32(4): e12954.

Marchitto MC, Dillen CA, Liu H, Miller RJ, Archer NK, Ortines RV, Alphonse MP, Marusina AI, Merleev AA, Wang Y, Pinsker BL, Byrd AS, Brown ID, Ravipati A, Zhang E, Cai SS, Limjunyawong N, Dong X, Yeaman MR, Simon SI, Shen W, Durum SK, O’Brien RL, Maverakis E, Miller LS. Clonal Vγ6+Vδ4+ T cells promote IL-17-mediated immunity against Staphylococcus aureus skin infectionPROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, 116(22): 10917-10926.

Le ST, Wang JZ, Alexanian CC, Johng SY, Patel FB, Wang EA, Ma C, Wilken R, Cheng MY, Maverakis EEnd stage scurvy in the developed world: A diagnostic conundrum but not to be mistaken for pyoderma gangrenosumInternational Wound Journal, 16(4): 1024-1028.

Kim B, Maverakis E, Raychaudhuri SP. Is It Possible to Discontinue Tumor Necrosis Factor Antagonists after Psoriasis Remission? Annals of Dermatology, doi.org/10.5021/ad.2019.31.5.495 [Epub ahead of print]

Weiss DI, Ma F, Merleev AA, Maverakis E, Gillet M, Balin SJ, Bryson BD, Ochoa MT, Pellegrini M, Bloom BR, Modlin RL. IL-1β Induces the Rapid Secretion of the Antimicrobial Protein IL-26 from Th17 Cells. Journal of Immunology, 203(4): 911-921.

Tuscano JM, Maverakis E, Groshen S, Tsao-Wei D, Luxardi G, Merleev A, Beaven AW, DiPersio JF, Popplewell L, Chen R, Kirschbaum M, Schroeder MA, Newman EM. A Phase I Study of the Combination of Rituximab and Ipilimumab in Patients with Relapsed/Refractory B-Cell LymphomaClinical Cancer Research, doi: 10.1158/1078-0432.CCR-19-0438. [Epub ahead of print]

Jagdeo J, Nguyen JK, Ho D, Wang EB, Austin E, Mamalis A, Kaur R, Kraeva E, Schulman JM, Li CS, Hwang ST, Wun T, Maverakis E, Isseroff RR. Safety of light emitting diode-red light on human skin: two randomized controlled trialsJournal of Biophotonics, e201960014.

Nguyen CT, Maverakis E, Eberl M, Adamopoulos IE. γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunitySeminars in Immunopathology, doi: 10.1007/s00281-019-00752-5. [Epub ahead of print]

Sun YH, Kao HKJ, Chang CW, Merleev AA, Overton JL, Pretto D, Yechikov S, Maverakis E, Chiamvimonvat N, Chan JW, Lieu DK. Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesisStem Cells, doi: 10.1002/stem.3085. [Epub ahead of print]

Marusina AI, Merleev AA, Luna JI, Olney L, Haigh NE, Yoon D, Guo C, Ovadia EM, Shimoda M, Luxardi G, Boddu S, Lal NN, Takada Y, Lam KS, Liu R, Isseroff RR, Sun Y, Le S, Nolta JA, Kloxin AM, and Maverakis ETunable hydrogels for mesenchymal stem cell delivery: integrin-induced transcriptome alterations and hydrogel optimization for human wound healing. Stem Cells, [In Press]

Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockadeNATURE MEDICINE, 25(1): 141-151.

Barton VR, Le ST, Wang JZ, Toussi A, Sood A, Maverakis E. Peristomal ulcers misdiagnosed as pyoderma gangrenosum: a common error. J Eur Acad Dermatol Venereol. 2020;34(2):e108–e110. doi:10.1111/jdv.16034

Wang EA, Kao J, Ma C, et al. Non-surgical management of primary invasive melanoma [published online ahead of print, 2019 Nov 20]. J Dermatolog Treat. 2019;1–4. doi:10.1080/09546634.2019.1687830

Tsoi LC, Rodriguez E, Stölzl D, et al. Progression of acute-to-chronic atopic dermatitis is associated with quantitative rather than qualitative changes in cytokine responses [published online ahead of print, 2019 Dec 28]. J Allergy Clin Immunol. 2019;S0091-6749(19)32610-7. doi:10.1016/j.jaci.2019.11.047

Khuat, Lam & Le, Catherine & Pai, Steven & Shields-Cutler, Robin & Holtan, Shernan & Rashidi, Armin & Parker, Sarah & Knights, Dan & Luna, Jesus Isaac & Dunai, Cordelia & Wang, Ziming & Sturgill, Ian & Stoffel, Kevin & Merleev, Alexander & Maverakis, Emanual & Raybould, Helen & Chen, Mingyi & Canter, Robert & Monjazeb, Arta & Murphy, William. (2019). Obesity-Induced Microbiome Alterations Result in Severe Gastrointestinal Graft-Versus-Host Disease Following Allogeneic Hematopoietic Stem Cell Transplantation. Blood. 134. 1922-1922. 10.1182/blood-2019-127743.


2018

Dillen CA, Pinsker BL, Marusina AI, Merleev AA, Farber ON, Liu H, Archer NK, Lee DB, Wang Y, Ortines RV, Lee SK, Marchitto MC, Cai SS, Ashbaugh AG, May LS, Holland SM, Freeman AF, Miller LG, Yeaman MR, Simon SI, Milner JD, Maverakis E, Miller LS. Clonally expanded γδ T cells protect against Staphylococcus aureus skin reinfection. JOURNAL OF CLINICAL INVESTIGATION, 128(3): 1026-1042.

Kao J, Wang EA, Cheng MY, Ma C, Kiuru M, Maverakis EExuberant scale crust of the scalp. JAAD Case Reports, 4(4): 289-291.

Ogawa H, Luxardi G, Kirane A, Kulkarni R, Monjazeb AM, Cheng MY, Ma C, Maverakis ET Cells Dominate the Local Immune Response Induced by Intralesional IL-2 in Combination with Imiquimod and Retinoid for In-Transit Metastatic Melanoma. The Journal of Investigative Dermatology, 138(6): 1442-1445.

Park DD, Xu G, Wong M, Phoomak C, Liu M, Haigh NE, Wongkham S, Yang P, Maverakis E, Lebrilla CB. Membrane glycomics reveal heterogeneity and quantitative distribution of cell surface sialylation. CHEMICAL SCIENCE, 9(29): 6271-6285.


Wang EA, Steel A, Luxardi G, Mitra A, Patel F, Cheng MY, Wilken R, Kao J, de Ga K, Sultani H, Merleev AA, Marusina AI, Brassard A, Fung MA, Konia T, Shimoda M, Maverakis EClassic Ulcerative Pyoderma Gangrenosum Is a T Cell-Mediated Disease Targeting Follicular Adnexal Structures: A Hypothesis Based on Molecular and Clinicopathologic Studies. Frontiers in Immunology, 8: 1980.

McGee HM, Daly ME, Azghadi S, Stewart SL, Oesterich L, Schlom J, Donahue R, Schoenfeld JD, Chen Q, Rao S, Fragoso RC, Valicenti RK, Canter, RJ, Maverakis EM, Murphy WJ, Kelly K, Monjazeb AM. Stereotactic Ablative Radiation Therapy Induces Systemic Differences in Peripheral Blood Immunophenotype Dependent on Irradiated Site. International Journal of Radiation Oncology, Biology, Physics, 101(5): 1259-1270.

Maverakis E, Ma C, Shinkai K, Fiorentino D, Callen JP, Wollina U, Marzano AV, Wallach D, Kim K, Schadt C, Ormerod A, Fung MA, Steel A, Patel F, Qin R, Craig F, Williams HC, Powell F, Merleev A, Cheng MY. Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts. JAMA Dermatology, 154(4): 461-466.

Wang EA, Maverakis EThe rapidly evolving lesions of ulcerative pyoderma gangrenosum: a timeline. International Journal of Dermatology, 57(8): 983-984.

Raychaudhuri SK, Abria C, Maverakis EM, Raychaudhuri SP. IL-9 receptor: Regulatory role on FLS and pannus formation. Cytokine, 111: 58-62.

Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis EMeta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A. JCI INSIGHT, 3(13).

LeValley PJ, Ovadia EM, Bresette CA, Sawicki LA, Maverakis E, Bai S, Kloxin AM. Design of functionalized cyclic peptides through orthogonal click reactions for cell culture and targeting applications. CHEMICAL COMMUNICATIONS, 54(50): 6923-6926.

Murrell DF, Peña S, Joly P, Marinovic B, Hashimoto T, Diaz LA, Sinha AA, Payne AS, Daneshpazhooh M, Eming R, Jonkman MF, Mimouni D, Borradori L, Kim SC, Yamagami J, Lehman JS, Saleh MA, Culton DA, Czernik A, Zone JJ, Fivenson D, Ujiie H, Wozniak K, Akman-Karakaş A, Bernard P, Korman NJ, Caux F, Drenovska K, Prost-Squarcioni C, Vassileva S, Feldman RJ, Cardones AR, Bauer J, Ioannides D, Jedlickova H, Palisson F, Patsatsi A, Uzun S, Yayli S, Zillikens D, Amagai M, Hertl M, Schmidt E, Aoki V, Grando SA, Shimizu H, Baum S, Cianchini G, Feliciani C, Iranzo P, Mascaró JM, Kowalewski C, Hall R, Groves R, Harman KE, Marinkovich MP, Maverakis E, Werth VP. Diagnosis and Management of Pemphigus: recommendations by an International Panel of Experts. Journal of the American Academy of Dermatology, doi: 10.1016/j.jaad.2018.02.021. [Epub ahead of print]

Armstrong AW, Chambers CJ, Maverakis E, Cheng MY, Dunnick CA, Chren MM, Gelfand JM, Wong DJ, Gibbons BM, Gibbons CM, Torres J, Steel AC, Wang EA, Clark CM, Singh S, Kornmehl HA, Wilken R, Florek AG, Ford AR, Ma C, Ehsani-Chimeh N, Boddu S, Fujita M, Young PM, Rivas-Sanchez C, Cornejo BI, Serna LC, Carlson ER, Lane CJ. Effectiveness of Online vs In-Person Care for Adults With Psoriasis: A Randomized Clinical TrialJAMA Network Open, 1(6):e183062.


2017

Patel F, Wilken R, Patel FB, Sultani H, Bustos I, Duong C, Zone JJ, Raychaudhuri SP, Maverakis EPathophysiology of Autoimmune Bullous Diseases: Nature Versus Nurture. Indian Journal of Dermatology, 62(3): 262-267.

Rehmann MS, Skeens KM, Kharkar PM, Ford EM, Maverakis E, Lee KH, Kloxin AM. Tuning and Predicting Mesh Size and Protein Release from Step Growth Hydrogels. Biomacromolecules, 18(10): 3131-3142.

Krishnan S, Shimoda M, Sacchi R, Kailemia MJ, Luxardi G, Kaysen GA, Parikh AN, Ngassam VN, Johansen K, Chertow GM, Grimes B, Smilowitz JT, Maverakis E, Lebrilla CB, Zivkovic AM. HDL Glycoprotein Composition and Site-Specific Glycosylation Differentiates Between Clinical Groups and Affects IL-6 Secretion in Lipopolysaccharide-Stimulated MonocytesScientific Reports, 7: 43728.

Maverakis E, Wang EA, Shinkai K, Mahasirimongkol S, Margolis DJ, Avigan M, Chung WH, Goldman J, La Grenade L, Pirmohamed M, Shear NH, Tassaeeyakul W, Hoetzenecker W, Klaewsongkram J, Rerkpattanapipat T, Manuyakorn W, Yasuda SU, Sharon VR, Sukhov A, Micheletti R, Struewing J, French LE, Cheng MY. Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Standard Reporting and Evaluation Guidelines: Results of a National Institutes of Health Working GroupJAMA Dermatology, 153(6): 587-592.

Wang EA, Kao J, Cheng MY, Ma C, Dhillon S, Konia T, Maverakis E, Chambers CJ. Severe pellagra masked by concurrent plaque psoriasis: a case report of a hidden diagnosis. Dermatology Online Journal, 23(5).

Bustos-Villalobos I, Bergstrom JW, Haigh NE, Luna JI, Mitra A Marusina AI, Merleev AA, Wang EA, Sukhov A, Sultani H, Liu R, Bhardwaj G, Guo W, Kung HJ, Lam KS, Maverakis EITK inhibition for the targeted treatment of CTCL. Journal of Dermatological Science, 87(1): 88-91.

Kharkar PM, Scott RA, Olney LP, LeValley PJ, Maverakis E, Kiick KL, Kloxin AM. Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. Advanced Healthcare Materials, 6(24).

Zhou F, Shimoda M, Olney L, Lyu Y, Tran K, Jiang G, Nakano K, Davis RR, Tepper CG, Maverakis E, Campbell M, Li Y, Dandekar S, Izumiya Y. Oncolytic Reactivation of KSHV as a Therapeutic Approach for Primary Effusion Lymphoma. Molecular Cancer Therapeutics, 16(11): 2627-2638.

Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis ECD4+ virtual memory: Antigen-inexperienced T cells reside in the naïve, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. Journal of Autoimmunity, 77: 76-88.

Wang EA, Suzuki E, Maverakis E, Adamopoulos IE. Targeting IL-17 in psoriatic arthritisEuropean Journal of Rheumatology, 4(4): 272-277.
  

2016

Marusina AI, Ono Y, Merleev AA, Shimoda M, Ogawa H, Wang EA, Kondo K, Olney L, Luxardi G, Miyamura Y, Yilma TD, Villalobos IB, Bergstrom JW, Kronenberg DG, Soulika AM, Adamopoulos IE, Maverakis E. CD4+ virtual memory: Antigen-inexperienced T cells reside in the naive, regulatory, and memory T cell compartments at similar frequencies, implications for autoimmunity. J Autoimmun. 2016.10.1016/j.jaut.2016.11.001

Raychaudhuri SP, Wilken R, Sukhov AC, Raychaudhuri SK, Maverakis E. Management of psoriatic arthritis: Early diagnosis, monitoring of disease severity and cutting edge therapies. J Autoimmun. 2017;76:21-37.10.1016/j.jaut.2016.10.009















2015

Wilken R, Sharma A, Patel F, Maverakis E. Successful treatment of palmoplantar pustulosis with isotretinoin. Dermatol Online J. 2015;21(8)


Wilken R, Li CS, Sharon VR, Kim K, Patel FB, Patel F, Maverakis E. Topical clobetasol for the treatment of toxic epidermal necrolysis: study protocol for a randomized controlled trial. Trials. 2015;16:374.10.1186/s13063-015-0879-7


Shi VY, Tran K, Patel F, Leventhal J, Konia T, Fung MA, Wilken R, Garcia MS, Fitzmaurice SD, Joo J, Monjazeb AM, Burrall BA, King B, Martinez S, Christensen SD, Maverakis E. 100% Complete response rate in patients with cutaneous metastatic melanoma treated with intralesional interleukin (IL)-2, imiquimod, and topical retinoid combination therapy: results of a case series. J Am Acad Dermatol. 2015;73(4):645-654.10.1016/j.jaad.2015.06.060


Patel F, Fitzmaurice S, Duong C, He Y, Fergus J, Raychaudhuri SP, Garcia MS, Maverakis E. Effective strategies for the management of pyoderma gangrenosum: a comprehensive review. Acta Derm Venereol. 2015;95(5):525-531.10.2340/00015555-2008



Park D, Brune KA, Mitra A, Marusina AI, Maverakis E, Lebrilla CB. Characteristic Changes in Cell Surface Glycosylation Accompany Intestinal Epithelial Cell (IEC) Differentiation: High Mannose Structures Dominate the Cell Surface Glycome of Undifferentiated Enterocytes. Mol Cell Proteomics. 2015;14(11):2910-2921.10.1074/mcp.M115.053983



Mitra A, Luna JI, Marusina AI, Merleev A, Kundu-Raychaudhuri S, Fiorentino D, Raychaudhuri SP, Maverakis E. Dual mTOR Inhibition Is Required to Prevent TGF-beta-Mediated Fibrosis: Implications for Scleroderma. J Invest Dermatol. 2015;135(11):2873-2876.10.1038/jid.2015.252


Maverakis E, Kim K, Shimoda M, Gershwin ME, Patel F, Wilken R, Raychaudhuri S, Ruhaak LR, Lebrilla CB. Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review. J Autoimmun. 2015;57:1-13.10.1016/j.jaut.2014.12.002

Maverakis E, Cornelius LA, Bowen GM, Phan T, Patel FB, Fitzmaurice S, He Y, Burrall B, Duong C, Kloxin AM, Sultani H, Wilken R, Martinez SR, Patel F. Metastatic melanoma - a review of current and future treatment options. Acta Derm Venereol. 2015;95(5):516-524.10.2340/00015555-2035



Hong Q, Ruhaak LR, Stroble C, Parker E, Huang J, Maverakis E, Lebrilla CB. A Method for Comprehensive Glycosite-Mapping and Direct Quantitation of Serum Glycoproteins. J Proteome Res. 2015;14(12):5179-5192.10.1021/acs.jproteome.5b00756


He Y, Shimoda M, Ono Y, Villalobos IB, Mitra A, Konia T, Grando SA, Zone JJ, Maverakis E. Persistence of Autoreactive IgA-Secreting B Cells Despite Multiple Immunosuppressive Medications Including Rituximab. JAMA Dermatol. 2015;151(6):646-650.10.1001/jamadermatol.2015.59


Adamopoulos IE, Suzuki E, Chao CC, Gorman D, Adda S, Maverakis E, Zarbalis K, Geissler R, Asio A, Blumenschein WM, McClanahan T, De Waal Malefyt R, Gershwin ME, Bowman EP. IL-17A gene transfer induces bone loss and epidermal hyperplasia associated with psoriatic arthritis. Ann Rheum Dis. 2015;74(6):1284-1292.10.1136/annrheumdis-2013-204782



2014

Armstrong AW, Johnson MA, Lin S, Maverakis E, Fazel N, Liu FT. Patient-centered, direct-access online care for management of atopic dermatitis: a randomized clinical trial. JAMA Dermatol. 2015;151(2):154-160.10.1001/jamadermatol.2014.2299

Wu DJ, Dixit N, Suzuki E, Nguyen T, Shin HS, Davis J, Maverakis E, Adamopoulos IE. A novel in vivo gene transfer technique and in vitro cell based assays for the study of bone loss in musculoskeletal disorders. J Vis Exp. 2014(88).10.3791/51810


Sharon V, Burrall B, Patel F, He Y, Konia T, Villalobos IB, Maverakis E. Multimodal therapy of idiopathic pyoderma gangrenosum. Dermatol Online J. 2014;20(6)


Raychaudhuri SK, Maverakis E, Raychaudhuri SP. Diagnosis and classification of psoriasis. Autoimmun Rev. 2014;13(4-5):490-495.10.1016/j.autrev.2014.01.008


Patel F, Wilken R, Burrall B, Martinez S, Wells V, King B, Maverakis E. Detailed protocol for administration of intralesional IL-2 for the treatment of Stage IIIc and IV M1a metastatic melanoma based on current NCCN guidelines. Dermatol Online J. 2014;20(11)

Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ. Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice. J Exp Med. 2014;211(12):2373-2383.10.1084/jem.20140116

Maverakis E, Patel F, Kronenberg DG, Chung L, Fiorentino D, Allanore Y, Guiducci S, Hesselstrand R, Hummers LK, Duong C, Kahaleh B, Macgregor A, Matucci-Cerinic M, Wollheim FA, Mayes MD, Gershwin ME. International consensus criteria for the diagnosis of Raynaud's phenomenon. J Autoimmun. 2014;48-49:60-65.10.1016/j.jaut.2014.01.020


Maverakis E, He Y, Patel FB, Fitzmaurice S, Fung MA. Mycobacterium chelonae infection presenting as recurrent cutaneous and subcutaneous nodules--a presentation previously diagnosed as Weber Christian disease. Dermatol Online J. 2014;20(6)


Prior to 2013

Sivamani RK, Goodarzi H, Garcia MS, Raychaudhuri SP, Wehrli LN, Ono Y, Maverakis E. Biologic therapies in the treatment of psoriasis: a comprehensive evidence-based basic science and clinical review and a practical guide to tuberculosis monitoring. Clin Rev Allergy Immunol. 2013;44(2):121-140.10.1007/s12016-012-8301-7


Shah DR, Yang AD, Maverakis E, Martinez SR. Assessing rural-urban disparities in the use of sentinel lymph node biopsy for melanoma. J Surg Res. 2013;184(2):1157-1160.10.1016/j.jss.2013.04.091


Shah DR, Yang AD, Maverakis E, Martinez SR. Age-related disparities in use of completion lymphadenectomy for melanoma sentinel lymph node metastasis. J Surg Res. 2013;185(1):240-244.10.1016/j.jss.2013.05.090


Patel F, Marusina AI, Duong C, Adamopoulos IE, Maverakis E. NKG2C, HLA-E and their association with psoriasis. Exp Dermatol. 2013;22(12):797-799.10.1111/exd.12280


Martinez SR, Shah DR, Yang AD, Canter RJ, Maverakis E. Sentinel lymph node biopsy in patients with thick primary cutaneous melanoma: patterns of use and underuse utilizing a population-based model. ISRN Dermatol. 2013;2013:315609.10.1155/2013/315609


He Y, Maverakis E, Ramirez-Maverakis D, Fitzmaurice S. Combination therapy with intralesional triamcinolone and oral dapsone for management of palisaded neutrophilic and granulomatous dermatitis. Dermatol Online J. 2013;19(2):17

Bouchlaka MN, Sckisel GD, Chen M, Mirsoian A, Zamora AE, Maverakis E, Wilkins DE, Alderson KL, Hsiao HH, Weiss JM, Monjazeb AM, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Redelman D, Taub DD, Murphy WJ. Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy. J Exp Med. 2013;210(11):2223-2237.10.1084/jem.20131219

Sivamani RK, Ma BR, Wehrli LN, Maverakis E. Phytochemicals and Naturally Derived Substances for Wound Healing. Adv Wound Care (New Rochelle). 2012;1(5):213-217.10.1089/wound.2011.0330


Sharon VR, Garcia MS, Bagheri S, Goodarzi H, Yang C, Ono Y, Maverakis E. Management of recalcitrant hidradenitis suppurativa with ustekinumab. Acta Derm Venereol. 2012;92(3):320-321.10.2340/00015555-1229


Revzin A, Maverakis E, Chang HC. Biosensors for immune cell analysis-A perspective. Biomicrofluidics. 2012;6(2):21301-2130113.10.1063/1.4706845


Maverakis E, Li CS, Alikhan A, Lin TC, Idriss N, Armstrong AW. The effect of academic "misrepresentation" on residency match outcomes. Dermatol Online J. 2012;18(1):1


Maverakis E, Goodarzi H, Wehrli LN, Ono Y, Garcia MS. The etiology of paraneoplastic autoimmunity. Clin Rev Allergy Immunol. 2012;42(2):135-144.10.1007/s12016-010-8248-5


Maverakis E. Sercarzian immunology--In memoriam. Eli E. Sercarz, 1934-2009. Cell Immunol. 2012;273(2):99-108.10.1016/j.cellimm.2011.12.009


Martinez SR, Shah DR, Maverakis E, Yang AD. Geographic variation in utilization of sentinel lymph node biopsy for intermediate thickness cutaneous melanoma. J Surg Oncol. 2012;106(7):807-810.10.1002/jso.23169


Loh E, Maverakis E, Konia T, Noll E. Lepromatous leprosy in a 26-year-old man with concurrent disseminated tuberculosis. Arch Dermatol. 2012;148(9):1096-1097.10.1001/archdermatol.2012.970


Loh E, Fung MA, Maverakis E. Acute guttate psoriasis in a 15-year-old girl with Epstein-Barr virus infection. Arch Dermatol. 2012;148(5):658-659.10.1001/archdermatol.2011.3517


Guo W, Liu R, Ono Y, Ma AH, Martinez A, Sanchez E, Wang Y, Huang W, Mazloom A, Li J, Ning J, Maverakis E, Lam KS, Kung HJ. Molecular characteristics of CTA056, a novel interleukin-2-inducible T-cell kinase inhibitor that selectively targets malignant T cells and modulates oncomirs. Mol Pharmacol. 2012;82(5):938-947.10.1124/mol.112.079889


Goodarzi H, Sivamani RK, Garcia MS, Wehrli LN, Craven H, Ono Y, Maverakis E. Effective Strategies for the Management of Pyoderma Gangrenosum. Adv Wound Care (New Rochelle). 2012;1(5):194-199.10.1089/wound.2011.0339


Bouchlaka MN, Sckisel GD, Wilkins D, Maverakis E, Monjazeb AM, Fung M, Welniak L, Redelman D, Fuchs A, Evrensel CA, Murphy WJ. Mechanical disruption of tumors by iron particles and magnetic field application results in increased anti-tumor immune responses. PLoS One. 2012;7(10):e48049.10.1371/journal.pone.0048049


Zhang W, Ono Y, Miyamura Y, Bowlus CL, Gershwin ME, Maverakis E. T cell clonal expansions detected in patients with primary biliary cirrhosis express CX3CR1. J Autoimmun. 2011;37(2):71-78.10.1016/j.jaut.2011.05.009


Rudolph M, Hebel K, Miyamura Y, Maverakis E, Brunner-Weinzierl MC. Blockade of CTLA-4 decreases the generation of multifunctional memory CD4+ T cells in vivo. J Immunol. 2011;186(10):5580-5589.10.4049/jimmunol.1003381


He Y, Merin MR, Sharon VR, Maverakis E. Eruptive keloids associated with breast cancer: a paraneoplastic phenomenon? Acta Derm Venereol. 2011;91(4):480-481.10.2340/00015555-1089


Garcia MS, Ono Y, Martinez SR, Chen SL, Goodarzi H, Phan T, Wehrli LN, Miyamura Y, Fung MA, Maverakis E. Complete regression of subcutaneous and cutaneous metastatic melanoma with high-dose intralesional interleukin 2 in combination with topical imiquimod and retinoid cream. Melanoma Res. 2011;21(3):235-243.10.1097/CMR.0b013e328345e95e


Takada Y, Ono Y, Saegusa J, Mitsiades C, Mitsiades N, Tsai J, He Y, Maningding E, Coleman A, Ramirez-Maverakis D, Rodrigues R, Takada Y, Maverakis E. A T cell-binding fragment of fibrinogen can prevent autoimmunity. J Autoimmun. 2010;34(4):453-459.10.1016/j.jaut.2009.11.017


Sivamani RK, Correa G, Ono Y, Bowen MP, Raychaudhuri SP, Maverakis E. Biological therapy of psoriasis. Indian J Dermatol. 2010;55(2):161-170.10.4103/0019-5154.62754


Maverakis E, Miyamura Y, Bowen MP, Correa G, Ono Y, Goodarzi H. Light, including ultraviolet.
J Autoimmun. 2010;34(3):J247-257.10.1016/j.jaut.2009.11.011
Maverakis E, Menezes JS, Ametani A, Han M, Stevens DB, He Y, Wang Y, Ono Y, Miyamura Y, Lam KS, Ward ES, Sercarz EE. Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity. Proc Natl Acad Sci U S A. 2010;107(6):2550-2555.10.1073/pnas.0914508107

Chen HY, Fermin A, Vardhana S, Weng IC, Lo KF, Chang EY, Maverakis E, Yang RY, Hsu DK, Dustin ML, Liu FT. Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse. Proc Natl Acad Sci U S A. 2009;106(34):14496-14501.10.1073/pnas.0903497106


Maverakis E, Beech JT, Schneider S, Sercarz EE. Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptide. J Autoimmun. 2008;31(1):59-65.10.1016/j.jaut.2008.02.004


Wadhera A, Maverakis E, Mitsiades N, Lara PN, Fung MA, Lynch PJ. Thymoma-associated multiorgan autoimmunity: a graft-versus-host-like disease. J Am Acad Dermatol. 2007;57(4):683-689.10.1016/j.jaad.2007.02.027

Menezes JS, van den Elzen P, Thornes J, Huffman D, Droin NM, Maverakis E, Sercarz EE. A public T cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE. J Clin Invest. 2007;117(8):2176-2185.10.1172/JCI28277


Maverakis E, Lynch PJ, Fazel N. Acrodermatitis enteropathica. Dermatol Online J. 2007;13(3):11


Maverakis E, Fung MA, Lynch PJ, Draznin M, Michael DJ, Ruben B, Fazel N. Acrodermatitis enteropathica and an overview of zinc metabolism. J Am Acad Dermatol. 2007;56(1):116-124.10.1016/j.jaad.2006.08.015


Kwak J, Maverakis E. Epidermolytic hyperkeratosis. Dermatol Online J. 2006;12(5):6


van den Elzen P, Menezes JS, Ametani A, Maverakis E, Madakamutil L, Tang XL, Kumar V, Sercarz EE. Limited clonality in autoimmunity: drivers and regulators. Autoimmun Rev. 2004;3(7-8):524-529.10.1016/j.autrev.2004.07.008


Sercarz EE, Maverakis E. Recognition and function in a degenerate immune system. Mol Immunol. 2004;40(14-15):1003-1008.10.1016/j.molimm.2003.11.002

Sercarz EE, Maverakis E. Mhc-guided processing: binding of large antigen fragments. Nat Rev Immunol. 2003;3(8):621-629.10.1038/nri1149


Sercarz E, Maverakis E, van den Elzen P, Madakamutil L, Kumar V. Seven surprises in the TCR-centred regulation of immune responsiveness in an autoimmune system. Novartis Found Symp. 2003;252:165-171; discussion 171-166, 203-110

Robinson WH, Fontoura P, Lee BJ, de Vegvar HE, Tom J, Pedotti R, DiGennaro CD, Mitchell DJ, Fong D, Ho PP, Ruiz PJ, Maverakis E, Stevens DB, Bernard CC, Martin R, Kuchroo VK, van Noort JM, Genain CP, Amor S, Olsson T, Utz PJ, Garren H, Steinman L. Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis. Nat Biotechnol. 2003;21(9):1033-1039.10.1038/nbt859

Maverakis E, Beech J, Stevens DB, Ametani A, Brossay L, van den Elzen P, Mendoza R, Thai Q, Macias LH, Ethell D, Campagnoni CW, Campagnoni AT, Sette A, Sercarz EE. Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC. Proc Natl Acad Sci U S A. 2003;100(9):5342-5347.10.1073/pnas.0936151100

Elewaut D, Lawton AP, Nagarajan NA, Maverakis E, Khurana A, Honing S, Benedict CA, Sercarz E, Bakke O, Kronenberg M, Prigozy TI. The adaptor protein AP-3 is required for CD1d-mediated antigen presentation of glycosphingolipids and development of Valpha14i NKT cells. J Exp Med. 2003;198(8):1133-1146.10.1084/jem.20030143


Ria F, van den Elzen P, Madakamutil LT, Miller JE, Maverakis E, Sercarz EE. Molecular characterization of the T cell repertoire using immunoscope analysis and its possible implementation in clinical practice. Curr Mol Med. 2001;1(3):297-304


Maverakis E, van den Elzen P, Sercarz EE. Self-reactive T cells and degeneracy of T cell recognition: evolving concepts-from sequence homology to shape mimicry and TCR flexibility. J Autoimmun. 2001;16(3):201-209.10.1006/jaut.2000.0493


Abromson-Leeman S, Maverakis E, Bronson R, Dorf ME. CD40-mediated activation of T cells accelerates, but is not required for, encephalitogenic potential of myelin basic protein-recognizing T cells in a model of progressive experimental autoimmune encephalomyelitis. Eur J Immunol. 2001;31(2):527-538.10.1002/1521-4141(200102)31:2<527::AID-IMMU527>3.0.CO;2-D


Wilson SS, van den Elzen P, Maverakis E, Beech JT, Braciak TA, Kumar V, Sercarz EE. Residual public repertoires to self. J Neuroimmunol. 2000;107(2):233-239


Maverakis E, Mendoza R, Southwood S, Raja-Gabaglia C, Abromson-Leeman S, Campagnoni AT, Sette A, Sercarz EE. Immunogenicity of self antigens is unrelated to MHC-binding affinity: T-cell determinant structure of Golli-MBP in the BALB/c mouse. J Autoimmun. 2000;15(3):315-322.10.1006/jaut.2000.0436



Maverakis E, Beech JT, Wilson SS, Quinn A, Pedersen B, Sercarz EE. T cell receptor complementarity determining region 3 length analysis reveals the absence of a characteristic public T cell repertoire in neonatal tolerance. The response in the "tolerant" mouse within the residual repertoire is quantitatively similar but qualitatively different. J Exp Med. 2000;191(4):695-702

38 comments:

  1. interested in tech news related with What Mobile Vivo


    ReplyDelete
    Replies
    1. I was cured of CANCER with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from CANCER for 3 yrs but with the help of Dr.Sayo herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from FIBROID, as soon as i heard she had FIBROID, i quickly refer her to Dr.Sayo and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Sayo and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Sayo now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Sayo have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr Sayo through his Email address on: sayoherbalhealer@gmail.com or WHATSAPP/CALL him on+2349012175679 Visit his FB page: https://www.facebook.com/Sayo-Herbal-Healer-100145798345000/    
      also visit website: http://sayoherbalhealinghome.com/ or check blogs: https://naturerootandherbscures.blogspot.com/ Please share the good news to other people once you are cured  

      Delete
    2. Are you heart broken or thinking of how you are to live the rest of your life with Herpes? I'm here to tell you to cry no more for Dr Osato is here to help you with the cure for herpes. I was diagnose of genital herpes November 2019 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Osato herbal medicine. I quickly contact Dr Osato on email (osatoherbalcure@gmail.com) and explain my problem to him and he prepare the herbs and send it to me through UPS and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE  and my doctor confirm with me that am completely free from herpes. I'm so happy and grateful to Dr Osato for curing me from herpes and i will continue to share this for people out there to know that there is cure for herpes. Dr Osato also have the cure for different type of diseases and virus like HERPES, HIV, HSV1&2, DIABETES, CANCER, HPV, Sickle Cell, Cold Sore ect. You can contact Dr Osato on email and WhatsApp.... Email: osatoherbalcure@gmail.com or WhatsApp +2347051705853.... Website: osatoherbalcure.wordpress.com.......

      Dr Osato herbal medicine is the best medicine for herpes and you can contact him today to get cured. 

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    3. Hello everyone i am Mudaf Kyle from MALARIA , i am here to give my testimony about a great Best Herbal Penis Enlargement Medicine    called Dr OLU, I was heartbroken and disappointed because i had very small penis, not big enough to satisfy or pregnant a woman, i have been in so many relationship, but cut off because of my small penis situation, i have used so many product,drugs,vaccines,herbs which doctors prescribe for me, but none could offer me the help i searched for. one faithful day i saw some few comments on the internet about how this great specialist called Dr OLU has been helping men enlarge their penis size ,pregnant woman and last longer in bed and i decided to email him on his email i saw on the internet,(drolusolutionhome@gmail.com) or you can also WhatasApp him  number +2348140654426so I decided to give his herbal product a try. i emailed him and he got back to me, he gave me some comforting words and steps to follow which i did with his herbal pills for Penis Enlargement, Within 1 week of it, i began to feel the enlargement of my penis, " and now it just 1 weeks of using his products my penis is about 10.5 inches longer in erection , and i had to settle out with my Ex girlfriend Stephanie, i was surprised when she opened her mouth and said that i almost killed her and she is satisfied with my sex and i have got a very Big penis now.Am so happy, thanks to Dr OLU I also learn that Dr OLU also help with
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    4. Joy and happiness is all i see around ever since i came in contact with this great man. i complained bitterly to him about me having herpes only for him to tell me it’s a minor stuff. He told me he has cured thousands of people but i did not believe until he sent me the herbal medicine and i took it as instructed by this great man, only to go to the hospital after two weeks for another test and i was confirmed negative. For the first time in four years i was getting that result. i want to use this medium to thank this great man. His name is Dr aziegbe, i came in contact with his email through a friend in UK and ever since then my live has been full with laughter and great peace of mind. i urge you all with herpes or HSV to contact him if you willing to give him a chance. you can contact him through this email DRAZIEGBE1SPELLHOME@GMAIL.COM or you can also WhatsApp him +2349035465208
      He also cured my friend with HIV and ever since then i strongly believe he can do all things. Don't be deceived thinking he does not work, i believe if you can get in contact with this man all your troubles will be over. i have done my part in spreading the good news. Contact him through his email and you will be the next to testify of his great work.

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    1. Are you heart broken or thinking of how you are to live the rest of your life with Herpes? I'm here to tell you to cry no more for Dr Osato is here to help you with the cure for herpes. I was diagnose of genital herpes November 2019 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Osato herbal medicine. I quickly contact Dr Osato on email (osatoherbalcure@gmail.com) and explain my problem to him and he prepare the herbs and send it to me through UPS and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE  and my doctor confirm with me that am completely free from herpes. I'm so happy and grateful to Dr Osato for curing me from herpes and i will continue to share this for people out there to know that there is cure for herpes. Dr Osato also have the cure for different type of diseases and virus like HERPES, HIV, HSV1&2, DIABETES, CANCER, HPV, Sickle Cell, Cold Sore ect. You can contact Dr Osato on email and WhatsApp.... Email: osatoherbalcure@gmail.com or WhatsApp +2347051705853.... Website: osatoherbalcure.wordpress.com.......

      Dr Osato herbal medicine is the best medicine for herpes and you can contact him today to get cured. 

      Delete
  3. I was cured of CANCER with the used of natural herbs. My name is celina jolly and am from US. I love herbs so much. Most times, injection and drugs are just a waste of time. I was cured 8 months ago, i suffered from CANCER for 3 yrs but with the help of Dr.Sayo herbal medicine, i was cured within few weeks of drinking the herbs he sent to me through courier delivery service. This same doctor also cured my Aunty from FIBROID, as soon as i heard she had FIBROID, i quickly refer her to Dr.Sayo and she was cured too after drinking his herbs.I have referred more than 15 persons to Dr.Sayo and they were all cured from their various illness. Have you taken herbs before?. You have spent so much money on drugs,injections,surgeries etc and yet you have no good result to show for it. Contact Dr. Sayo now, he is a herbalist doctor, i assured you of a cure if you drink his natural herbs. Dr.Sayo have herbs that cures Hiv, Herpes, diabetics, asthma, hepatitis, HBP, STD, cancer, chronic, etc. Contact Dr Sayo through his Email address on: sayoherbalhealer@gmail.com or WHATSAPP/CALL him on+2349012175679 Visit his FB page: https://www.facebook.com/Sayo-Herbal-Healer-100145798345000/    
    also visit website: http://sayoherbalhealinghome.com/ or check blogs: https://naturerootandherbscures.blogspot.com/ Please share the good news to other people once you are cured  

    ReplyDelete
  4. My Profound and Utmost Gratitude to Doctor Razor, I am here to Share my testimony about a doctor who helped me remove a burden from my life. I was diagnosed with HSV 1 on March 17, 2017, i didn't bother seeking for medical aide because i know that the Government And medical Scientists Have been lying to us about herpes not Having a complete Cure, so I was thinking of how to get a solution, To make sure i get this Infection out of my body. I went to visiting a friend of mine who happens to be A family friend as well and she asked why i was looking so sad, i explained to her my problem, she told me that she can help me out, she introduced me to a doctor who uses herbal medication to cure HERPES SIMPLEX VIRUS and gave me his email, as well as his Website : https://drrazorherbalhome.wixsite.com/drrazorherbalhome . So I emailed him. He told me all the things I needed to do and also gave me instructions on How i was to take the medicine For 18 days, which I followed properly. After completion of the Dosage the herbalist Requested that i go for a medical Test And i was amazed after my Test Result came out Negative. If you are also heart broken and also need help, you can also email him at: drrazorherbalhome@gmail.com . Whatsapp/Call Doctor Razor via +2349065420442

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  5. I'm 40 years old female I tested genital herpes (HSV1-2) positive in 2002. I was having bad outbreaks. EXTREMELY PAINFUL. I have try different kinds of drugs and treatment by the medical doctors all to know was avail. Six months ago I was desperately online searching for a helpful remedies for genital herpes (HSV1-2) cure, which i come across some helpful remedies on how Dr OYAGU have help so many people in curing genital herpes (HSV1-2) with the help of herbal treatment because I too believe there is someone somewhere in the world who can cure herpes completely. At of the past 2 months, however, I've been following his herpes protocol Via oyaguherbalhome@gmail.com or +2348101755322 and it stopped all outbreaks completely! To my greatest surprise I was cured completely by following the protocol of his herbal medicine . Don't be discouraged by the medical doctors. There is a cure for HSV with the help of herbs and roots by a herbalist Dr call Dr OYAGU he is so kind and truthful with his herbal treatment, kindly contact him for more information Via oyaguherbalhome@gmail.com or WhatsApp DR on +2348101755322 you will be lucky as i am today

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  6. I'm 40 years old female I tested genital herpes (HSV1-2) positive in 2002. I was having bad outbreaks. EXTREMELY PAINFUL. I have try different kinds of drugs and treatment by the medical doctors all to know was avail. Six months ago I was desperately online searching for a helpful remedies for genital herpes (HSV1-2) cure, which i come across some helpful remedies on how Dr OYAGU have help so many people in curing genital herpes (HSV1-2) with the help of herbal treatment because I too believe there is someone somewhere in the world who can cure herpes completely. At of the past 2 months, however, I've been following his herpes protocol Via oyaguherbalhome@gmail.com or +2348101755322 and it stopped all outbreaks completely! To my greatest surprise I was cured completely by following the protocol of his herbal medicine . Don't be discouraged by the medical doctors. There is a cure for HSV with the help of herbs and roots by a herbalist Dr call Dr OYAGU he is so kind and truthful with his herbal treatment, kindly contact him for more information Via oyaguherbalhome@gmail.com or WhatsApp DR on +2348101755322 you will be lucky as i am today

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  7. Am testifying of the miraculous work of a great traditional doctor called  Dr Maggi. I have been suffering from herpes since last 2 years with my Husband but today I am happy that am cure from it with the herbal medicine made by  Dr Maggi   the great healer, I was browsing the Internet searching for help when I came across a testimony shared by someone on how  Dr Maggi cure her from Herpes Disease. I quickly contacted him to get the cure and today i am now free from the Virus,drmaggiherbalhome@gmail.com you can also call or whatsApp him on +1(917) 979-6387

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  11. NATURAL HERPES CURE.Herpes simplex virus is said to have no cure, just as i was told by my family doctor that herpes can not be cured but can be controlled, Although i was a very stubborn person i never believed in what my doctor told me about herpes having no cure. Am a very honest person who believe in nature and i also believed that there could be cure somewhere in the world, I kept my faith so strong and kept on doing my research till i saw an article shared by a testifier on How a herbal Doctor Razor from west Africa, i Decided to use his herbal medicine, so i Reached out to him and explained my situation to him, he promised to guide me, after 4 days of reaching out to him i received my medication sent to me by Doctor Razor and he instructed me to use it for 18 days, After Completion of his herbal medicine dosage, i went for a medical checkup as i was told by Doctor Razor. I am so happy and extremely excited that I got cured of this Virus. Massive gratitude to doctor Razor. Reach out to him via his clinic email : drrazorherbalhome@gmail.com  On whatsapp/call his cell phone +2349065420442. Together we stand a chance to fight herpes. Let's continue to share this till The whole world Gets to know that there is a herbal cure for herpes.God bless you all.

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  12. I was able to get rid of my herpes virus this year, i was diagnosed of herpes virus since late 2015 and i was on my doctor prescription ever since i have the virus, I wasn’t satisfied i needed to get the virus out of my system and get rid of the virus,i was going through a blog to find new informations about the Herpes Simplex Virus i came across a review of a lady who was testify on the  cured that the great herbalist cured is virus and  i have to contert him and see what he told me to do for me to get rid of the cure I contacted the herbal foundation and they guided me on how to purchase the herbal formula. the herbal products las me for 3 weeks which helps me to get rid of the virus totally, for easy communication you can reach Dr Freeman Osas on his WhatSapp via +2347057052206 email. balogospellcaster@gmail.com     

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  13. I was able to get rid of my herpes virus this year, i was diagnosed of herpes virus since late 2015 and i was on my doctor prescription ever since i have the virus, I wasn’t satisfied i needed to get the virus out of my system and get rid of the virus,i was going through a blog to find new informations about the Herpes Simplex Virus i came across a review of a lady who was testify on the  cured that the great herbalist cured is virus and  i have to contert him and see what he told me to do for me to get rid of the cure I contacted the herbal foundation and they guided me on how to purchase the herbal formula. the herbal products las me for 3 weeks which helps me to get rid of the virus totally, for easy communication you can reach Dr Freeman Osas on his WhatSapp via +2347057052206 email. balogospellcaster@gmail.com     

    ReplyDelete
  14. I was able to get rid of my herpes virus this year, i was diagnosed of herpes virus since late 2015 and i was on my doctor prescription ever since i have the virus, I wasn’t satisfied i needed to get the virus out of my system and get rid of the virus,i was going through a blog to find new informations about the Herpes Simplex Virus i came across a review of a lady who was testify on the  cured that the great herbalist cured is virus and  i have to contert him and see what he told me to do for me to get rid of the cure I contacted the herbal foundation and they guided me on how to purchase the herbal formula. the herbal products las me for 3 weeks which helps me to get rid of the virus totally, for easy communication you can reach Dr Freeman Osas on his WhatSapp via +2347057052206 email. balogospellcaster@gmail.com     

    ReplyDelete
  15. God bless Dr Uromi for his marvelous work in my life, I have been suffering from herpes virus since 2015 and I was taking my medications, and I wasn't really satisfied i needed to get this disease out of my system, I searched about some possible cure for herpes and hsv infections online when i saw some wonderful comments about Dr Uromi, how he cured hsv infections with his herbal medicine, I was relieve a little so I contacted him through the emaiL i got from the testifier, and i told him my problem and asked for solutions, he told he can help cure me completely if only i can trust him to work for me and i said yes i can and immediately he started the remedy for my health, and after which he sent me the medicine through UPS SPEED POST. I took the herbal remedy as directed by him and 14 days later i was cured from my herpes infection, thank you so much sir, so my dear viewers online if you have or know anyone out there suffering from Hsv, Herpes, Cold Sore, Fibroids, Anemia, Hiv etc i urged you to recommend them to Dr Uromi and i assure you he will be of great help. you can reach Dr Uromi on Email:: Druromiherbalhome@gmail.com . You can also add him on WhatsApp +2349021374574    .   

    ReplyDelete
  16. HOW I GOT CURED FROM HERPES SIMPLEX VIRUS:
    God bless  Dr Oje Abacha  for his marvelous work in my life, I was diagnosed of HERPES since 2016 and I was taking my medications, I wasn’t satisfied, i needed to get the HERPES out of my system, I was directed by my brother in-law to meet  Dr Oje Abacha     who is good at curing HERPES DIABETES and CANCER with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS delivery service (UPS). I took the medicine as prescribed by him and 13 days later i was cured from HERPES, by Dr Oje Abacha   truly you are great, do you need his help also? Why don’t you contact him through email:  oje.herbalsolutioncentre@gmail.com  Or contact him on whatapp via +2348159734766 . https://ojeherbalsolutioncentre.wordpress.com  

    ReplyDelete

  17. Hello everyone my name is Alex Macron, i am from USA...
    I'm here to testify about the great work DR.BALBOSA did for me. I have been suffering from (GENITAL HERPES HSV-2) disease for the past 3 years and had constant pains and depressed. During the first year,I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from various doctors, few weeks ago i came across a testimony of someone on the internet testifying about a Man called Dr.BALBOSA on how he cured her from Herpes Simplex Virus. And she also gave the email address of this man and advise anybody with same issue to contact him for help for any kind of sickness that he would be of help, so I emailed him telling him about my (HERPES Virus) he told me not to worry that i was going to be cured!! Well i never believed it because i was in doubt. well after all the procedures and remedy given to me by this man which i took for 3 weeks,few months later i started experiencing changes all over me as Dr.BALBOSA assured me that i will be cured,after some time i went to my doctor to confirmed if i have been healed, behold it was TRUE and the doctor was even suprised and ask me how i was healed...So i decided to share this wonderful testimony online to everyone suffering from any type of HERPES.. friends my advise is if you have such sickness or any other at all you can contact Dr BALBOSA via email balbosaherbalhome@gmail.com....GOODLUCK....
    Contact DR.BALBOSA ON EMAIL: balbosaherbalhome@gmail.com
    Whatsapp contact: +2347048047728



    Hello everyone my name is Alex Macron, i am from USA...
    I'm here to testify about the great work DR.BALBOSA did for me. I have been suffering from (GENITAL HERPES HSV-2) disease for the past 3 years and had constant pains and depressed. During the first year,I had faith in God that i would be healed someday.This disease started circulating all over my body and i have been taking treatment from various doctors, few weeks ago i came across a testimony of someone on the internet testifying about a Man called Dr.BALBOSA on how he cured her from Herpes Simplex Virus. And she also gave the email address of this man and advise anybody with same issue to contact him for help for any kind of sickness that he would be of help, so I emailed him telling him about my (HERPES Virus) he told me not to worry that i was going to be cured!! Well i never believed it because i was in doubt. well after all the procedures and remedy given to me by this man which i took for 3 weeks,few months later i started experiencing changes all over me as Dr.BALBOSA assured me that i will be cured,after some time i went to my doctor to confirmed if i have been healed, behold it was TRUE and the doctor was even suprised and ask me how i was healed...So i decided to share this wonderful testimony online to everyone suffering from any type of HERPES.. friends my advise is if you have such sickness or any other at all you can contact Dr BALBOSA via email balbosaherbalhome@gmail.com....GOODLUCK....
    Contact DR.BALBOSA ON EMAIL: balbosaherbalhome@gmail.com
    Whatsapp contact: +2347048047728

    ReplyDelete
  18. Please share as you read okay you may save a soul today, natural herbs
    are really great, I was cured from HSV by a doctor called DR Okiti from West Africa, now I believe that natural herbs and roots has their own way of working, based on medical report I was told that HSV has no cure even when I saw a post about Dr Okiti how he cured many people with his herbal medicine I doubted it at first but just decided to give it a try because I was so desperately trying to get rid of my problems not knowing it was going to be the end of this deadly virus in my body, please if you have anyone with this same virus or diseases like this contact Dr Okiti via email drokitiherbalhome100@gmail.com or whatsapp +234 705 067 0365. I'm a living testimony of his herbal medicine and don't forget to share as you read okay, please save a soul today.

    ReplyDelete
  19. Are you heart broken or thinking of how you are to live the rest of your life with Herpes? I'm here to tell you to cry no more for Dr Osato is here to help you with the cure for herpes. I was diagnose of genital herpes November 2019 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Osato herbal medicine. I quickly contact Dr Osato on email (osatoherbalcure@gmail.com) and explain my problem to him and he prepare the herbs and send it to me through UPS and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE  and my doctor confirm with me that am completely free from herpes. I'm so happy and grateful to Dr Osato for curing me from herpes and i will continue to share this for people out there to know that there is cure for herpes. Dr Osato also have the cure for different type of diseases and virus like HERPES, HIV, HSV1&2, DIABETES, CANCER, HPV, Sickle Cell, Cold Sore ect. You can contact Dr Osato on email and WhatsApp.... Email: osatoherbalcure@gmail.com or WhatsApp +2347051705853.... Website: osatoherbalcure.wordpress.com.......

    Dr Osato herbal medicine is the best medicine for herpes and you can contact him today to get cured. 

    ReplyDelete
  20. Are you heart broken or thinking of how you are to live the rest of your life with Herpes? I'm here to tell you to cry no more for Dr Osato is here to help you with the cure for herpes. I was diagnose of genital herpes November 2019 and i have been searching and asking questions to see if i could get something to cure the disease because i did not believe what the doctors say that no cure is found yet. I came across a comment on Youtube and the person testify how she was cured from herpes and hpv after using Dr Osato herbal medicine. I quickly contact Dr Osato on email (osatoherbalcure@gmail.com) and explain my problem to him and he prepare the herbs and send it to me through UPS and gave me instructions on how to use it and tell me to go for checkup after usage which i did after two weeks of taken the herbal medicine and my result was NEGATIVE  and my doctor confirm with me that am completely free from herpes. I'm so happy and grateful to Dr Osato for curing me from herpes and i will continue to share this for people out there to know that there is cure for herpes. Dr Osato also have the cure for different type of diseases and virus like HERPES, HIV, HSV1&2, DIABETES, CANCER, HPV, Sickle Cell, Cold Sore ect. You can contact Dr Osato on email and WhatsApp.... Email: osatoherbalcure@gmail.com or WhatsApp +2347051705853.... Website: osatoherbalcure.wordpress.com.......

    Dr Osato herbal medicine is the best medicine for herpes and you can contact him today to get cured. 

    ReplyDelete
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  22. ALL THANKS TO GOD FOR WHAT HER HAS DONE FOR ME FOR USING DOCTOR RAZOR TO HEAL ME OF MY HERPES INFECTION WITH HIS QUICK CURE FOR HERPES. I have read so much on Herpes Simplex virus. I hear of reaching clearance, I hear of no cure, I hear of recurrent lesions, poor immune system, poor diet, etc. I just do not know what to believe. I have visited many web pages that seem to sell you their version of removing or enforcing the immune system. Then I hear all the info on therapeutic vaccines as well as prophylactic vaccines and wonder how can that even help me. And I feel so worthless, Glad i came across Doctor Razor article on how to heal HSV forever. Endless Gratitude to doctor Razor for helping me get rid of my Herpes Virus Ever since being infected November 13, 2018 . Reach him on his clinic email drrazorherbalhome@gmail.com
    Whatsapp His cell phone on +2349065420442Website : https://herbalistrazorherb.wixsite.com/drrazorherbalhome

    ReplyDelete
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  24. Do You Need A Powerful Africa Native Doctor? I Mean A Spiritual Herbalist
    With Great Spirit Connected To Ancestors. Call or WhatsApp +2349058774809 Dr Obodubu Monday Is A High Voodoo Priest Master. He is a Spell Caster, Native
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    Money Ritual.
    Have You Been To Native Doctor to Native Doctor Without Any Solution To
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    Bad Dream
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    Spiritual Attack
    Land/Court Case
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    Political Appointment
    Visa Approval
    Cancer
    Examination Success
    Spend And Get Back
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    Hypertension
    Diabesity (Diabetic+Obesity
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  28. Never give up in life they all say no cure to Herpes Virus which is a big lie I have pass through many process also i never believe there is really cure to HERPES until I meet Dr. Kham the doctor that have been helping many people for many years, I come across this doctor online when I was searching for cure online I found out about this man, and to my greatest surprise this man have the herbal medicine which I have been looking for years I explain my problem to him through the email I found on someone who testify about him also, Dr. Kham write me a reply and explain how the process work so after ordering for the medicine I got it within 4 days and I took it according to the way Dr. Kham instructed, I was so happy after two week I took the medicine there was very big change in my health when I was done with the process I go for test, I found out I am negative that was the day I have the tears of joy you can also get in contact with my doctor through his email now dr.khamcaregiver@gmail.com or you can also WhatsApp him +2348159922297, You can Also Visit his website to know more about him at > https://drkhamherbalhealingcenter.wordpress.com/ or https://drkhamcaregiver.wixsite.com/drkhamcaregiverherba He also have herbs medicine to cured the following diseases; eczema,urethra wart,chronic problems.Herpes, Cancer, Als,Hepatitis, Diabetes, HPV, HIV, Diabetes, Fibroid, Infections,ulcer ETC

    ReplyDelete
  29. Joy and happiness is all i see around ever since i came in contact with this great man. i complained bitterly to him about me having herpes only for him to tell me it’s a minor stuff. He told me he has cured thousands of people but i did not believe until he sent me the herbal medicine and i took it as instructed by this great man, only to go to the hospital after two weeks for another test and i was confirmed negative. For the first time in four years i was getting that result. i want to use this medium to thank this great man. His name is Dr aziegbe, i came in contact with his email through a friend in UK and ever since then my live has been full with laughter and great peace of mind. i urge you all with herpes or HSV to contact him if you willing to give him a chance. you can contact him through this email DRAZIEGBE1SPELLHOME@GMAIL.COM or you can also WhatsApp him +2349035465208
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    ReplyDelete
    Replies
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  30. My name is susan , i’m from UK. i have heard lots of stories about spell casters but never believed in them, not until recently when i had a problem with my husband who was cheating on me secretly. I tried all i could within my powers to stop him from seeing somebody outside but it yielded no good results. Then i read some posts of some persons about how DR EKPOMA spells actually works, i read that he casts a variety of spells like LOVE SPELLS, GETTING EX BACK SPELLS, MONEY SPELLS, EMPLOYMENT SPELLS, VISION SPELLS and many others, just to mention a few. So i decided to try him out, but to my greatest surprise it worked out perfectly and what amazes me the most is that his spells are free. Now i and my husband are happy once again thanks to DR EKPOMA . You can contact him at drekpoma77temple@gmail.com call or
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  31. DR Abubaka herbal medicine is the best remedy for Herpes and HIV/AIDS, I was a carrier of Herpes and I saw a testimony on how Dr. Abubaka cure Herpes, I decided to have a contact with him and asked him for solutions and he started the remedy for my health and prepare the herbal cure for me which i use to cure myself. Thank God, now everything is fine, I'm cured by Dr. Abubaka herbal medicine, I'm very thankful to Dr. Abubaka and i will not stop publishing his name on the internet because of the good work he did for me, You can reach him on his email: DrAbubaka@gmail.com or WhatsApp: +2348075551672

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  32. I want to share this wonderful testimony to the Good people all over the world on how I was able to Enlarge my Penis by Dr. Aziba. I was living a shameful life from my young age, just last month as I was browsing on the internet about Penis size  and Enlargement Products, I saw a testimony of a Man called Tim James testifying of how he was able to get his penis Enlarged by Dr. Aziba and I decided to also Email Dr. Aziba for my small penis size and he quickly respond to me and gave me the normal instructions which i did and then he shipped the product to me here in the united state which i received in just 3 working days and today i am very happy because i started seeing positive changes in my penis size in just 7 days of use.  Dr Aziba herbal product is the best recommended for you and to whom ever suffering from this shame or having any other diseases as well should Contact this great herbal doctor via his Email : Priestazibasolutioncenter@gmail.com and WhatsApp Him on +2348100368288

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