Saturday, August 22, 2015
In this article we put forth the Glycan Theory of Autoimmunity, which states that each autoimmune disease will have a unique glycan signature. We also review how glycans are important components of the immune system and how they bestow effector function to a variety of molecules.
J Autoimmun. 2015 Feb;57:1-13. doi: 10.1016/j.jaut.2014.12.002. Epub 2015 Jan 9.
Below is a link to the article. Please take a look!
Tuesday, August 18, 2015
Dual mTOR Inhibition Is Required to Prevent TGF-β-Mediated Fibrosis: Implications for Scleroderma
In this article we demonstrated that dual mTOR inhibition can prevent TGF-beta-inudced fibrosis. These results have implications for scleroderma.
J Invest Dermatol. 2015 Jul 2. doi: 10.1038/jid.2015.252. [Epub ahead of print]
Thursday, August 13, 2015
100% Complete response rate in patients with cutaneous metastatic melanoma treated with intralesional interleukin (IL)-2, imiquimod, and topical retinoid combination therapy: Results of a case series
In this article we report the results of 11 melanoma patients treated with intralesional IL-2 with imiquimod for in-transit mets.The combination therapy worked very well. Link to Article